Related Experiment Video
Updated: Aug 15, 2026

Two-photon Imaging of Cellular Dynamics in the Mouse Spinal Cord
Published on: February 23, 2015
[Role of immunoregulatory cells and natural killers in the pathogenesis of multiple sclerosis]
Abstract:
Simultaneous investigations of the immunoregulatory cells and the natural killers were carried out in patients with different stages of multiple sclerosis in an attempt to determine a relationship between these organisms and the clinical stage of the disease. The quantities of E- and EAC-RFC in patients of all groups were within normal. The amount of T gamma-cells was decreased in the progressive phase of the disease and was significantly higher than normal during remission. The activity of the natural killers in the progressive phase of disease did not differ from control but was significantly depressed during remission with all effector/target ratios. The activity of the natural killers and the amount of T gamma-cells were found to be reversely correlated both in the progressive and remission phases of the disease. A quantitative reduction in the 0 population of lymphocytes was accompanied by a sharp suppression of natural killer activity.
More Related Videos
08:47Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
Published on: May 8, 2016
09:38Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
Published on: September 12, 2016
Related Concept Videos
Cell-mediated Immune Responses
Cells of the Innate Immune Response
Phagocytes
Phagocytes police the peripheral tissues by removing cellular debris and responding to the invasion of foreign substances or pathogens. Many phagocytes attack and remove microorganisms even before lymphocytes detect them. The human body has two general...
Immune Surveillance by NK Cells and Phagocytes
Natural Killer Cells: The Fast Responders
NK cells are large granular lymphocytes found in the blood and lymphatic system. These...
T Cell Types and Functions
Th1 cells stimulate dendritic cells to express necessary co-stimulatory molecules on their surfaces for...
Cytotoxic T Cells-mediated Immune Response
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
Immune Response Against Viral Pathogens
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...