[Treatment of sex offenses with antiandrogens]

A review of the literature published during the past ten years reveals a clear drop in the number of publications on the treatment of sexual deviations with antiandrogens. Although only one double-blind study has been published so far, we can safely say on the basis of the other experience reports that the antiandrogen Cyproterone acetate reduces appetence in males and also that this effect is reversible, besides an established good body tolerance of the preparation. At first, the spectrum of indications was very broad, and it is now markedly narrowed down, although it is still very inhomogeneous. The need of combining treatment with antiandrogens with psychotherapeutic measures has been generally recognized. Catamnestic reports are extremely rare. This means we are unable to give a satisfactory answer to essential questions, such as the range of indication, the duration of treatment with the preparation under discussion, the number of relapses after discontinuing the administration, etc. Further research in this field is imperative.