Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Deep innervation of sural nerve.

S C Chang, J Y Wei, C P Mao

    Brain Research
    |November 21, 1983
    PubMed
    Summary

    Stimulating subcutaneous tissues activated 37 sural nerve fibers, with slower fibers showing higher activation thresholds. Many A delta and C fibers exhibited prolonged afterdischarges following repeated stimulation.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    [Study on mechanical properties of through-the-scope airway stents and complications caused by TTS airway stents in rabbits trachea].

    Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases·2025
    Same author

    [Develop and assessment of a predictive model for the first-course efficacy of acute myeloid leukemia].

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2025
    Same author

    [Effect and molecular mechanism of hesperadin-induced ferroptosis in chronic myeloid leukemia K562 cells].

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2024
    Same author

    Deciphering the <i>in situ</i> phonon evolution of potassium sodium niobate under varying temperature and electric fields.

    Physical chemistry chemical physics : PCCP·2024
    Same author

    [A comparison of R-CHOP and R-DA-EPOCH as a first-line regimen treatment of diffuse large B cell lymphoma with non-GCB subtypes: a retrospective study].

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2022
    Same author

    [Clinical characteristics and prognostic factors of 40 cases of primary systemic anaplastic large cell lymphoma].

    Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2020

    Area of Science:

    • Neuroscience
    • Somatosensory research
    • Peripheral nerve physiology

    Background:

    • Sural nerve afferents transmit sensory information from the lower leg.
    • Understanding the response properties of these afferents is crucial for pain and touch research.

    Purpose of the Study:

    • To characterize the response properties of sural afferents to subcutaneous tissue stimulation.
    • To investigate the relationship between conduction velocity, mechanical threshold, and afterdischarge characteristics.

    Main Methods:

    • Recording of 37 sural afferent fibers (A alpha to C range) in response to subcutaneous tissue stimulation after skin removal.
    • Assessment of mechanical excitability via muscle stretching.
    • Analysis of persistent afterdischarge following repeated stimulation.

    Main Results:

    • Most recorded fibers were not readily excited by muscle stretching, except for one A alpha unit with muscle spindle properties.
    • A trend of higher mechanical thresholds was observed in slower conducting fibers (A delta and C fibers).
    • Repeated stimulation induced persistent afterdischarges in the majority of A delta and C units, lasting from minutes to over 30 minutes.

    Conclusions:

    • Sural afferents exhibit diverse responses to mechanical stimuli applied to subcutaneous tissues.
    • Conduction velocity is inversely related to mechanical threshold in these afferents.
    • A delta and C fiber afferents are prone to developing prolonged afterdischarges, suggesting potential roles in persistent pain states.

    Related Experiment Videos