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Hydronephrosis, renal agenesis, and associated genitourinary anomalies in ACI rats

F F Marshall, R Garcia-Bunuel, D S Beisel

    Urology
    |January 1, 1978
    PubMed

    Abstract:

    The ACI rat provides a congenital mammalian model for the spontaneously occurring defects of renal agenesis and hydronephrosis. These anomalies appear to be part of a spectrum of abnormalities caused by a mesonephric duct defect. These same anomalies also exist in man probably more commonly than previously appreciated.

    Keywords:
    congenital urogenital anomaliesmammalian developmental modelmesonephric duct defectspontaneous renal malformations

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