Association of hepatitis B vaccine with other vaccines--laboratory animals study

The interactions of HB vaccine with other vaccines was studied according to a plan of simultaneous injections on animals in order to ascertain if it would be possible to include HB vaccine in the expanded programmes of vaccination in children in Africa. Investigations were made to discover if the immunogenicity of each vaccine, injected simultaneously with the Hepatitis B vaccine, was at least equal to its immunogenicity when injected alone. The vaccines studied in association with Hepatitis B were: BCG, DPT-Polio or DPT Measles, and Yellow Fever Vaccines.