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Flow Cytometry to Estimate Leukemia Stem Cells in Primary Acute Myeloid Leukemia and in Patient-derived-xenografts, at Diagnosis and Follow Up
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[Thrombocythemia with Philadelphia chromosome. Secondary appearance of chronic myeloid leukemia]

J P Vannier, G Schaison, F Valensi

    Presse Medicale (Paris, France : 1983)
    |November 19, 1983
    PubMed

    The finding of a Philadelphia chromosome in a case of apparently primary thrombocythaemia should change the diagnosis for that of chronic myeloid leukaemia. This theoretical view is supported by the case reported here, where a Philadelphia-chromosome was detected in the bone marrow cells of a patient with severe thrombocythaemia; a typical myeloid leukaemia developed 21 months after the onset of the disease; survival was of short duration.

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