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Mortality and late-onset affective disorder.

N J Evans, F A Whitlock

    Journal of Affective Disorders
    |November 1, 1983
    PubMed
    Summary

    Depression in males is linked to a shorter life expectancy. A 5-year study found higher mortality from natural causes in men with early or late-onset depression, not those without prior depression.

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    Area of Science:

    • Psychiatry
    • Epidemiology
    • Public Health

    Background:

    • Psychiatric conditions increase physical illness risks.
    • Depression in males is associated with reduced life expectancy.
    • The relationship between depression onset and mortality requires further investigation.

    Purpose of the Study:

    • To investigate the association between depression onset and all-cause mortality in males.
    • To determine if individuals without prior depression are at higher risk of mortality.

    Main Methods:

    • A 5-year follow-up study was conducted.
    • Mortality data from male patients were analyzed.
    • The study compared mortality rates based on depression onset (early vs. late) and history.

    Main Results:

    • A higher overall mortality from natural causes was observed in male patients with both early and late-onset depression.
    • The study did not confirm that individuals without prior depression were at greater risk of dying.

    Conclusions:

    • Depression, regardless of onset timing, is associated with increased mortality in males.
    • The findings suggest depression is a significant factor in male mortality, not merely a precursor to fatal illness.

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