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[Chronic endocarditis on valve prosthesis. 6 cases].

S Witchitz, F Fraisse, E Bouvet

    Presse Medicale (Paris, France : 1983)
    |February 4, 1984
    PubMed
    Summary
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    Chronic endocarditis following intracardiac prosthesis implantation presents significant challenges, often involving multiple relapses and severe complications. Continuous bacteriostatic antibiotic therapy showed promise in managing persistent or relapsed cases.

    Area of Science:

    • Cardiology
    • Infectious Diseases
    • Prosthetic Valve Endocarditis

    Background:

    • Intracardiac prosthesis implantation is associated with a risk of endocarditis.
    • Chronic endocarditis, defined as infection lasting over one year, poses unique management difficulties.

    Observation:

    • This study reviewed six cases of chronic endocarditis occurring 6 months to 2 years post-valve replacement.
    • Prosthetic materials included Starr-Edwards and Hancock valves, and an intracardiac patch.
    • Common microorganisms involved were Streptococcus, Serratia, and Corynebacterium.

    Findings:

    • Patients experienced 2-5 relapses over 18 months to 5 years.
    • Major complications included dysimmune syndrome, embolic events, and prosthesis disinsertion.

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  • Antibiotic therapy and surgery were employed, with recurrent disinsertion noted in surgical cases.

    • Implications:

    • Chronic endocarditis after prosthesis implantation has a high complication rate.
    • Continuous bacteriostatic antibiotics may be beneficial for persistent or relapsing infections.
    • Further research is needed to optimize treatment strategies for this challenging condition.