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Defective regulation of erythrocyte autoantibodies in SJL mice
Immunology
|March 1, 1984
Abstract:
When SJL mice are hyperimmunized with rat red blood cells (RBC), tolerance to self is readily broken and these animals develop a high autoantibody response to their own RBC. However, these mice also fail to generate those antigen-specific suppressor cells which normally regulate this induced autoantibody response.
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