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Malignant melanomas in farm animals.
Morphologie Et Embryologie
|July 1, 1983
Summary
This study describes malignant melanomas in horses, cattle, and pigs. The research details the disease
Area of Science:
- Veterinary Pathology
- Comparative Oncology
Background:
- Malignant melanoma is a neoplastic proliferation of melanocytes.
- This condition affects various animal species, presenting diverse clinical and pathological features.
Purpose of the Study:
- To describe the pathological characteristics of malignant melanomas in equids, bovines, and swine.
- To investigate the microscopic and ultrastructural features of these tumors.
Main Methods:
- Histopathological examination of tumor tissues.
- Electron microscopy to analyze cellular structures and melanosomes.
Main Results:
- In horses (5), tumors were tegumentally located and generalized, with microscopic findings including pigment cells and multinucleated cells. Hypophyseal microcysts and an adenoma were noted.
- In cattle (1 calf, 1 cow), generalized visceral malignant melanomas were observed, with cerebral involvement in one cow.
- In swine (2), malignant melanomas showed visceral generalization in a Duroc and cutaneous localization in a Bazna.
Conclusions:
- Malignant melanomas exhibit varied presentations and localizations across different animal species.
- Ultrastructural analysis revealed differentiated melanophores and melanophages with characteristic melanosomes.