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Published on: August 30, 2016
Home-testing for recurrent bacteriuria, using nitrite strips
Insights
Home testing for recurrent urinary infections in children using nitrite strips is effective. Parents successfully detected most infections, simplifying follow-up care for pediatric bacteriuria.
Area of Science:
- Pediatric Nephrology
- Clinical Microbiology
- Diagnostic Testing
Background:
- Recurrent urinary infections pose challenges for pediatric follow-up.
- Accurate home-based testing could simplify monitoring for bacteriuria in children.
Purpose of the Study:
- To evaluate the reliability of home-based nitrite test strips for detecting urinary tract infections in girls with recurrent infections.
- To assess parental compliance and the efficacy of home testing in identifying bacteriuria.
Main Methods:
- Nitrite test strips were provided to parents of 30 girls with recurrent urinary infections.
- Home testing of first-voided urine was performed twice weekly.
- Infections were confirmed via dip slides or urine colony counts (>10^5 bacteria/mL).
Main Results:
- 80% of families complied with the home testing protocol over an average of 11 months.
- Home testing detected 93% of bacteriuria episodes (28 out of 30).
- No false-positive results were recorded, and urinary nitrate was consistently present.
Conclusions:
- Twice-weekly home nitrite testing is a reliable method for detecting bacteriuria in children with recurrent urinary infections.
- Motivated parents can effectively use nitrite test strips for home follow-up, simplifying pediatric UTI management.
- The nitrite test is a valuable tool for at-home monitoring of children at high risk for recurrent bacteriuria.
Abstract:
Follow-up of children with recurrent urinary infections would be simplified by an accurate home-testing program for detection of infection. We provided nitrite test strips to the parents of 30 girls with recurrent urinary infection to determine if twice weekly home testing of first-voided urine could reliably detect infection. Infections were documented by dip slides or colony counts indicating more than 10(5) bacteria per milliliter of urine. Twenty-four families (80%) complied over a mean study period of 11 months, detecting 28 of 30 episodes of bacteriuria (93%). No false-positive tests occurred. Urinary nitrate, the substrate for nitrite production by bacteria, was universally present (greater than 100 microgram/ml) in 80 children. The nitrite test is useful for home follow-up observation of children at high risk of bacteriuria if applied repeatedly by motivated parents.
Related Concept Videos
Urinary Tract Infection I: Introduction
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care
Acute Pyelonephritis II: Diagnostic Studies and Management
Urine Studies I: Urinalysis
Urine Studies II: Urine Culture and Sensitivity Test

