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Dysfunctional endometrium in primary and secondary sterility. An optic and electronmicroscopic study
Morphologie Et Embryologie
|January 1, 1984
Summary
Endometrial dysfunction in women with infertility is characterized by disrupted cyclical maturation. Endometrium biopsy is crucial for diagnosing these dysfunctions and assessing ovarian function.
Area of Science:
- Reproductive biology
- Gynecology
- Pathology
Background:
- Primary and secondary sterility in women are often linked to endometrial factors.
- Understanding endometrial receptivity is key to diagnosing infertility.
Purpose of the Study:
- To investigate morphological, optical, and ultrastructural changes in endometria of infertile women.
- To identify key modifications in dysfunctional endometria.
Main Methods:
- Morphological, optical, and ultrastructural analysis of endometrial biopsies.
- Clinical and paraclinical selection of patients with primary and secondary sterility.
Main Results:
- Dysfunctional endometria exhibit perturbed cyclical maturation of epitheliostromal components.
- Maturation may be synergistic or dissociated, out of phase with the menstrual cycle.
- Perturbations are associated with luteal deficit, hormonal imbalances, receptivity disorders, and inflammation.
Conclusions:
- Endometrium biopsy is the optimal method for diagnosing endometrial dysfunctions.
- Biopsy reveals ovarian hormonal function and endometrial receptor qualities.
- Diagnosis requires correlating biopsy findings with clinical data.