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Restrictive cardiomyopathy.

J R Benotti, W Grossman

Annual Review of Medicine

|January 1, 1984

Summary

This summary is machine-generated.

Restrictive cardiomyopathy is a clinical syndrome caused by heart muscle thickening or infiltration. A precise diagnosis requires excluding pericardial constriction and confirming the restrictive process via biopsy, though often elusive.

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Area of Science:

Cardiology
Pathophysiology
Clinical Medicine

Background:

Restrictive cardiomyopathy presents as a clinical and hemodynamic syndrome.
It is characterized by myocardial hypertrophy or infiltrative processes leading to cardiocirculatory morbidity.

Purpose of the Study:

To define the diagnostic criteria and therapeutic approach for restrictive cardiomyopathy.
To emphasize the pathophysiologic mechanisms involved.

Main Methods:

Diagnosis requires exclusion of pericardial constriction.
Confirmation involves identifying the restrictive process through myocardial biopsy.
Extensive hemodynamic and histologic investigations are employed.

Main Results:

While rare infiltrative entities can cause restrictive cardiomyopathy, a definitive pathologic diagnosis is often not established.
The syndrome is characterized by specific pathophysiologic mechanisms.

Conclusions:

A precise diagnosis of restrictive cardiomyopathy necessitates excluding pericardial constriction and confirming the restrictive process via biopsy.
Despite diagnostic challenges, a therapeutic trial with a calcium entry blocking agent is recommended.