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Orbital involvement in multiple myeloma. A new angiographic presentation
Journal of Clinical Neuro-Ophthalmology
|March 1, 1984
Summary
Orbital plasmacytoma, a rare plasma cell tumor, can mimic other orbital tumors like meningiomas on imaging. Definitive diagnosis of this rare condition requires histopathologic examination.
Area of Science:
- Ophthalmology
- Oncology
- Radiology
Background:
- Orbital tumors present a diagnostic challenge, often requiring advanced imaging and histopathology.
- Plasmacytomas are malignant plasma cell neoplasms that can affect various sites, including the orbit.
Observation:
- A 49-year-old female presented with proptosis, orbital pain, decreased visual acuity, and a frontal bone mass.
- Radiographic imaging (CT, angiography) suggested a meningioma, but the lesion was avascular, which is atypical for plasmacytoma.
Findings:
- Histopathologic examination after craniotomy revealed the orbital mass to be a plasmacytoma.
- Bone marrow biopsy confirmed systemic multiple myeloma.
Implications:
- Orbital plasmacytomas can radiographically mimic other orbital malignancies, including meningiomas, melanomas, and carcinomas.
- This case underscores the critical role of histopathologic study for accurate diagnosis of orbital lesions.
- Awareness of atypical presentations is crucial for appropriate patient management.