Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optic neuritis in inflammatory bowel disease.

L A Sedwick, T G Klingele, R M Burde

    Journal of Clinical Neuro-Ophthalmology
    |March 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Disruption of mGluR5 in parvalbumin-positive interneurons induces core features of neurodevelopmental disorders.

    Molecular psychiatry·2015
    Same author

    Effect of galnon on induction of long-term potentiation in dentate gyrus of C57BL/6 mice.

    Neuropeptides·2005
    Same author

    Role of galanin receptor 1 and galanin receptor 2 activation in synaptic plasticity associated with 3',5'-cyclic AMP response element-binding protein phosphorylation in the dentate gyrus: studies with a galanin receptor 2 agonist and galanin receptor 1 knockout mice.

    Neuroscience·2005
    Same author

    Interleukin-1beta enhances NMDA receptor-mediated intracellular calcium increase through activation of the Src family of kinases.

    The Journal of neuroscience : the official journal of the Society for Neuroscience·2003
    Same author

    An interview with Ronald M. Burde, MD, outgoing editor-in-chief (1994-2001), Journal of Neuro-Ophthalmology by Jonathan A. Trobe.

    Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2001
    Same author

    Zinc induces a Src family kinase-mediated up-regulation of NMDA receptor activity and excitotoxicity.

    Proceedings of the National Academy of Sciences of the United States of America·2001
    Same journal

    An unusual cause of recurrent vitreous hemorrhage.

    Journal of clinical neuro-ophthalmology·1993
    Same journal

    History of the Frank B. Walsh Society.

    Journal of clinical neuro-ophthalmology·1993
    Same journal

    Digoxin toxicity. Recognizing the varied visual presentations.

    Journal of clinical neuro-ophthalmology·1993
    Same journal

    Duane's syndrome with giant aneurysm of the vertebral basilar arterial junction.

    Journal of clinical neuro-ophthalmology·1993
    Same journal

    Recovery of vision in a 47-year-old man with fulminant giant cell arteritis.

    Journal of clinical neuro-ophthalmology·1993
    Same journal

    Botulinum toxin type A in upper lid retraction of Graves' ophthalmopathy.

    Journal of clinical neuro-ophthalmology·1993
    See all related articles

    Inflammatory bowel disease can cause various eye problems. This study highlights optic neuropathy as a potential sole ocular manifestation in five ulcerative colitis patients.

    Area of Science:

    • Ophthalmology
    • Gastroenterology
    • Immunology

    Background:

    • Inflammatory bowel disease (IBD) encompasses chronic gastrointestinal inflammatory conditions.
    • Ocular manifestations are recognized complications of IBD, ranging from anterior to posterior segment involvement.
    • The spectrum of eye conditions associated with IBD includes keratitis, conjunctivitis, episcleritis, iritis, and neuroretinitis.

    Observation:

    • This report details five cases of patients with ulcerative colitis (UC).
    • All five patients presented with optic neuropathy.
    • Optic neuropathy was the only identified ocular manifestation in these cases.

    Findings:

    • Optic neuropathy can be a significant ocular complication of inflammatory bowel disease.
    • Ulcerative colitis, a form of IBD, was associated with optic neuropathy in the presented cases.

    Related Experiment Videos

  • In some instances, optic neuropathy may be the exclusive ocular sign of IBD.

    • Implications:

    • Clinicians should consider optic neuropathy in the differential diagnosis of ocular symptoms in IBD patients.
    • Early recognition and management of optic neuropathy may be crucial for preserving vision in IBD patients.
    • This emphasizes the importance of a multidisciplinary approach involving ophthalmologists and gastroenterologists for managing IBD-associated eye conditions.