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Opsoclonus. Update on clinical and pathologic associations.

G R Kilgo, G M Schwartze

    Journal of Clinical Neuro-Ophthalmology
    |June 1, 1984
    PubMed
    Summary
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    Opsoclonus, a rapid eye movement disorder, can be linked to various conditions but lacks defined pathology. This case report reviews adult opsoclonus and autopsy findings.

    Area of Science:

    • Neurology
    • Ophthalmology

    Background:

    • Opsoclonus is characterized by rapid, involuntary, conjugate eye movements.
    • This oculomotor disturbance is clinically associated with infections, neoplasms, toxins, and drugs.

    Observation:

    • A specific case of opsoclonus with postmortem results is presented.
    • The pathological examination revealed no consistently defined structural lesion.

    Findings:

    • Review of adult opsoclonus cases and available autopsy data.
    • Analysis of the relationship between clinical associations and pathological findings in opsoclonus.

    Implications:

    • Highlights the need for further research into the underlying pathophysiology of opsoclonus.
    • Emphasizes the importance of comprehensive postmortem analysis in understanding rare neurological disorders.

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