Immunoreactive copper-zinc superoxide-dismutase (SOD-1) in mosaic trisomy 21 and normal subjects

Copper-zinc superoxide-dismutase (SOD-1) (E.C. 1.15.11) levels were measured in 9 children with mosaic trisomy 21 as identified by R, H, G-banding technics. Radioimmunoassay of erythrocytes and fibroblasts did not demonstrate any significant correlation between levels of SOD-1 and percentage of trisomic 21 cells in the two target cell populations studied.