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[Cardiovascular changes in acromegaly. Prospective study].

E Badui, C González, D García Rubi

    Archivos Del Instituto De Cardiologia De Mexico
    |May 1, 1984
    PubMed
    Summary
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    Acromegaly frequently causes cardiovascular complications, including left ventricular hypertrophy and abnormal electrocardiograms. Treatment like hypophysectomy can reverse many cardiac issues, but not all.

    Area of Science:

    • Cardiology
    • Endocrinology
    • Pulmonology

    Context:

    • Acromegaly, a condition caused by excess growth hormone, significantly impacts cardiovascular health.
    • Non-invasive methods are crucial for assessing complications in acromegaly patients.

    Purpose:

    • To determine the frequency of cardiovascular complications in acromegaly patients using non-invasive methods.
    • To evaluate the effectiveness of hypophysectomy in reversing cardiac complications.

    Summary:

    • Seventy-one percent of 38 acromegaly patients exhibited cardiovascular alterations.
    • Left ventricular hypertrophy (68%) and abnormal electrocardiograms (71%) were common, with echocardiography being highly sensitive.
    • Pulmonary fibrosis, chronic bronchitis, and arterial hypertension were also prevalent; hypophysectomy showed significant regression of cardiac issues.

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    Impact:

    • Highlights the high prevalence of cardiovascular disease in acromegaly.
    • Demonstrates the efficacy of hypophysectomy in managing acromegaly-related cardiac complications.
    • Emphasizes the importance of regular cardiovascular monitoring for acromegaly patients.