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[Arthritis related to intestinal anastomoses]
Revue Du Rhumatisme Et Des Maladies Osteo-Articulaires
|October 1, 1976
Summary
Jejuno-colic and jejuno-ileal anastomoses can cause arthritis due to bacterial overgrowth. Restoring intestinal continuity effectively resolves these joint issues in difficult cases.
Area of Science:
- Gastroenterology
- Rheumatology
- Microbiology
Background:
- Jejuno-colic and jejuno-ileal anastomoses are surgical connections between the small and large intestines.
- These anastomoses have been associated with the development of arthritis.
- A specific physiopathology involving immune complexes has been identified as a cause.
Purpose of the Study:
- To investigate the link between intestinal anastomoses and arthritis.
- To elucidate the underlying pathogenic mechanisms.
- To evaluate treatment strategies for this condition.
Main Methods:
- Review of clinical cases presenting with arthritis post-intestinal anastomosis.
- Analysis of the role of bacterial overgrowth, specifically Escherichia coli and Bacillus fragilis.
- Assessment of therapeutic interventions, including surgical repair.
Main Results:
- Arthritis associated with jejuno-colic and jejuno-ileal anastomoses is linked to immune complexes.
- Bacterial pullulation of Escherichia coli and Bacillus fragilis contributes to the immune complex formation.
- Surgical re-establishment of intestinal continuity led to the resolution of joint symptoms.
Conclusions:
- Arthritis following intestinal anastomosis is an immune complex-mediated condition.
- Bacterial overgrowth plays a critical role in the pathogenesis.
- Restoring intestinal continuity is an effective treatment for refractory cases.