Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Skeletal changes associated with vascular malformations.

J B Boyd, J B Mulliken, L B Kaban

    Plastic and Reconstructive Surgery
    |December 1, 1984
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Techniques and results of palate fistula repair following palatoplasty: a 234-case multicenter study.

    Cirugia pediatrica : organo oficial de la Sociedad Espanola de Cirugia Pediatrica·2020
    Same author

    The colourful history of malachite green: from ancient Egypt to modern surgery.

    International journal of oral and maxillofacial surgery·2016
    Same author

    A loss of FUS/TLS function leads to impaired cellular proliferation.

    Cell death & disease·2014
    Same author

    Propranolol targets the contractility of infantile haemangioma-derived pericytes.

    The British journal of dermatology·2014
    Same author

    Mutations in the VEGFR3 signaling pathway explain 36% of familial lymphedema.

    Molecular syndromology·2013
    Same author

    Vascular cutaneous anomalies in children: malformations and hemangiomas.

    Pediatric surgery international·2013

    Vascular malformations, unlike hemangiomas, frequently cause bony alterations. These skeletal changes vary by malformation type, suggesting diverse underlying mechanisms impacting bone development.

    Area of Science:

    • Vascular Biology
    • Skeletal Development
    • Pediatric Radiology

    Background:

    • Birthmarks encompass hemangiomas and vascular malformations, which can affect skeletal development.
    • Understanding the specific impact of different birthmark types on bone is crucial for diagnosis and management.

    Purpose of the Study:

    • To investigate the association between different types of birthmarks (hemangiomas and vascular malformations) and bony alterations.
    • To characterize the specific skeletal changes associated with various vascular malformations.

    Main Methods:

    • Retrospective review of 580 birthmarks, categorizing them into hemangiomas (356) and vascular malformations (224).
    • Analysis of associated bony alterations, classifying them by size, shape, and density.
    • Correlation of specific bony changes with subtypes of vascular malformations.

    Related Experiment Videos

    Main Results:

    • Bony alterations were rare in hemangiomas (1%) but common in vascular malformations (34%).
    • Lymphatic malformations were associated with hypertrophy and distortion.
    • Extremity venous malformations showed hypoplasia and demineralization.
    • Arterial/high-flow lesions exhibited destructive and intraosseous changes.

    Conclusions:

    • Vascular malformations are significantly associated with diverse bony alterations, unlike hemangiomas.
    • The type of skeletal change correlates with the specific subtype of vascular malformation.
    • Mechanical, physiological, and developmental mechanisms likely contribute to altered skeletal growth.