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Related Experiment Videos

A non-invasive CSF flowmeter.

M Numoto, M Hara, T Sakai

    Journal of Medical Engineering & Technology
    |September 1, 1984
    PubMed
    Summary
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    A novel non-invasive device measures cerebrospinal fluid (CSF) flow in shunts using electrolysis-generated bubbles. This breakthrough offers accurate CSF flow monitoring for hydrocephalus management.

    Area of Science:

    • Biomedical Engineering
    • Medical Devices
    • Fluid Dynamics

    Background:

    • Hydrocephalus requires monitoring cerebrospinal fluid (CSF) flow in shunts.
    • Current monitoring methods can be invasive or lack precision.
    • Accurate CSF flow measurement is crucial for effective hydrocephalus treatment.

    Purpose of the Study:

    • To develop and validate a non-invasive method for quantitative CSF flow measurement in ventriculo-peritoneal shunts.
    • To assess the accuracy and range of the new method in both animal models and clinical settings.

    Main Methods:

    • An implantable device generates a bubble in the shunt tubing via electrolysis.
    • Bubble detection is achieved using electric impedance or ultrasonic Doppler probes.
    • Extracorporeal high-frequency transmission provides energy for electrolysis.

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  • CSF flow rate is calculated based on the velocity of the detected bubble.

    • Main Results:

    • Animal experiments demonstrated statistically accurate CSF flow measurements between 0.01 and 1.00 ml/min.
    • Clinical evaluation in 11 cases showed observed CSF flow rates ranging from 0.01 to 1.93 ml/min.
    • The method proved effective across a wide range of physiological flow rates.

    Conclusions:

    • The developed non-invasive method provides accurate quantitative measurement of CSF flow in shunt tubing.
    • This technology has significant potential for improving the management of hydrocephalus.
    • The technique offers a reliable alternative for monitoring shunt function non-invasively.