Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Schistosomal glomerular disease (a review).

Z A Andrade, E Van Marck

    Memorias Do Instituto Oswaldo Cruz
    |October 1, 1984
    PubMed
    Summary

    Schistosomal glomerulopathy is an immune-complex kidney disease affecting 12-15% of individuals with schistosomiasis. Antigens and antibodies form immune complexes in the glomerulus, leading to kidney damage.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Diagnosis of Cutaneous T-Cell Lymphoma Detecting T-Cell Receptor γ Chain Gene Monoclonality By Denaturing Gradient Gel Electrophoresis.

    Acta clinica Belgica·2016
    Same author

    The immune reconstitution inflammatory syndrome: a cause of death in persons on antiretroviral therapy?

    Acta clinica Belgica·2014
    Same author

    A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population.

    Obesity (Silver Spring, Md.)·2013
    Same author

    Excessive eosinophilia as paraneoplastic syndrome in a patient with non-small-cell lung carcinoma: a case report and review of the literature.

    Acta clinica Belgica·2011
    Same author

    High prevalence of advanced fibrosis in association with the metabolic syndrome in a Belgian prospective cohort of NAFLD patients with elevated ALT. Results of the Belgian NAFLD registry.

    Acta gastro-enterologica Belgica·2011
    Same author

    KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis.

    British journal of cancer·2010

    Area of Science:

    • Nephrology
    • Immunology
    • Parasitology

    Background:

    • Schistosomal glomerulopathy is a kidney disease associated with schistosomiasis.
    • It affects 12-15% of patients with hepatosplenic schistosomiasis.
    • Portal hypertension facilitates antigen-antibody complex formation in circulation.

    Purpose of the Study:

    • To define schistosomal glomerulopathy as an immune-complex disease.
    • To describe its pathogenesis, clinical presentation, and renal pathology.
    • To review the role of schistosomal antigens in glomerular injury.

    Main Methods:

    • Review of existing literature on schistosomal glomerulopathy.
    • Analysis of pathological findings in affected individuals.
    • Experimental models demonstrating immune complex deposition.

    Main Results:

    • Schistosomal glomerulopathy is characterized by chronic membranous-proliferative glomerulonephritis.
    • Nephrotic syndrome is the common clinical presentation.
    • Glomerular lesions contain schistosomal antigens, antibodies, and complement.

    Conclusions:

    • Schistosomal glomerulopathy is an immune-complex mediated renal disease.
    • Specific treatment for schistosomiasis may not impact the course of nephropathy.
    • Understanding the immunopathogenesis is crucial for managing kidney complications.

    Related Experiment Videos