Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Peripheral neuropathy associated with ethambutol.

V S Nair, M LeBrun, I Kass

    Chest
    |January 1, 1980
    PubMed
    Summary

    Ethambutol can cause peripheral neuropathy and optic neuritis in patients with drug-resistant tuberculosis. Early neuropathy symptoms may warn of impending vision loss, necessitating prompt drug withdrawal.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    PIGO Gene Variants: New Insights Into Prenatal Diagnosis.

    Prenatal diagnosis·2025
    Same author

    Effectiveness of SplashGuard Caregiver prototype in reducing the risk of aerosol transmission in intensive care unit rooms of SARS-CoV-2 patients: a prospective and simulation study.

    The Journal of hospital infection·2023
    Same author

    The Frequency of Germline BRCA and Non-BRCA HR-Gene-Variants in a Cohort of Pancreatic Cancer Patients.

    Digestive diseases and sciences·2022
    Same author

    Bayesian latent class analysis of the characteristics of diagnostic tests to assess the passive immunity transfer status in neonatal Belgian Blue beef calves.

    Preventive veterinary medicine·2022
    Same author

    Transfer kinetics of labeled aroma compounds from liquid media into coffee beans during simulated wet processing conditions.

    Food chemistry·2020
    Same author

    Potential use of biochar, compost and iron grit associated with Trifolium repens to stabilize Pb and As on a multi-contaminated technosol.

    Ecotoxicology and environmental safety·2019

    Area of Science:

    • Neurology
    • Ophthalmology
    • Infectious Diseases

    Background:

    • Drug-resistant tuberculosis (DR-TB) requires multi-drug regimens, often including ethambutol.
    • Ethambutol is a key second-line agent for DR-TB treatment.
    • Neurological and visual toxicities are known side effects of ethambutol.

    Observation:

    • A patient undergoing ethambutol retreatment for DR-TB developed peripheral neuropathy.
    • Optic neuritis subsequently developed in the same patient.
    • Neuropathy and ocular symptoms resolved after ethambutol discontinuation.

    Findings:

    • Peripheral neuropathy symptoms can precede ethambutol-induced optic neuritis by months.
    • This sequence suggests neuropathy as a potential early warning sign.
    • Prompt drug withdrawal is crucial for managing ethambutol toxicity.

    Implications:

    • Clinicians should monitor for peripheral neuropathy in patients on ethambutol.
    • Early recognition of neuropathy may prevent severe visual impairment.
    • This case highlights the importance of vigilant monitoring for ethambutol-related toxicities.

    Related Experiment Videos