Immunoglobulin E and A levels in atopic and anaphylactic children

Seventy-six children between 18 months and 12 years of age were included in this study. Sixty-one were atopic and 15 had anaphylaxis due to bee stings or drugs. Immunoglobulins: A, G. M and E were determined and evaluated with respect to age and diagnosis. IgA levels were lower in atopic children between six and ten years than in normals. IgE levels were high in both atopic and anaphylactic patients but higher in the atopic than in the anaphylactic group. The results are discussed, focusing on the question of basic immunologic impairment in allergy.