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Paradoxical effect of naloxone on nitrous oxide analgesia in man
European Journal of Pharmacology
|January 25, 1980
Abstract:
The effect of naloxone on nitrous oxide analgesia in man has been investigated. The paradoxical response so obtained indicates the possibility of a dural system mediating the pain response in man. These results support previous animal experiments indicating that nitrous oxide analgesia is mediated by the opiate receptors.