Clinical importance of the diagnosis of trophoblastic pseudotumors

Trophoblastic pseudotumor, a type of gestational trophoblastic neoplasia, is discussed in the context of a case report. The criteria for diagnosis, lack of placental villi, cytotrophoblast, extensive hemorrhage, and necrosis, can only be fulfilled on histopathologic study of a hysterectomy specimen. Clinical management should be based on the titer of the beta subunit of human chorionic gonadotropin, not on the type of gestational trophoblastic neoplasia.