Myeloid body associations in the frog pigment epithelium

Myeloid bodies are found in the retinal pigment epithelium of certain vertebrate species. They are organized structural forms of the smooth endoplasmic reticulum which are usually seen as stacks of flattened, smooth saccules having a circular or lens-shaped configuration. Our findings in the frog Rana pipiens suggest that changes occur in the structure of the myeloid bodies which are related to the phase of the diurnal lighting cycle. At certain times, the myeloid bodies are found closely associated with other cytoplasmic organelles, notably the nucleus and oil droplet. In addition these associations can be induced by incubation of the isolated eyecup in the presence of guanosine 3',5'-monophosphate.