Scirrhous carcinoma of the pyloric channel and distal antrum

The clinical, endoscopic, and pathologic features of 13 cases of scirrhous carcinoma of the pyloric channel and distal antrum are described and correlated with the radiographic findings. The lesions appear as smooth concentric narrowings, rigid and generally short. They are associated with outlet obstruction but without gastric or duodenal ulcerations. Features highly suggestive of pyloric muscular hypertrophy, such as indentation at the base of the duodenal cap and pyloric notch, may occur. Almost all cases had serosal invasion and lymphatic spread at surgery. The differential diagnosis and a short review of the pertinent literature is presented.