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The nasopharyngeal angiofibroma
Archives of Otolaryngology (Chicago, Ill. : 1960)
|April 1, 1980
Summary
Radiotherapy effectively treats nasopharyngeal angiofibroma, with 80% of first-time patients showing long-term tumor control. Repeat treatments or surgery may be needed for persistent tumors.
Area of Science:
- Otolaryngology
- Radiation Oncology
- Oncology
Background:
- Nasopharyngeal angiofibroma is a rare, benign tumor.
- Treatment options include surgery and radiotherapy.
Purpose of the Study:
- To evaluate the efficacy of radiotherapy for nasopharyngeal angiofibroma.
- To assess long-term tumor control and outcomes.
Main Methods:
- Retrospective review of 48 patients treated between 1948 and 1975.
- Radiotherapy administered at 3,000 rads over three weeks.
- Coronal tomography used to assess tumor extension.
Main Results:
- Radiotherapy achieved clinical and radiological control in 80% of 35 primary patients.
- Tumor regression observed, with a latent period up to two years.
- Seven of ten recurrent cases were controlled with re-irradiation; three required surgery.
Conclusions:
- Radiotherapy is a primary treatment for nasopharyngeal angiofibroma.
- Long-term tumor control is achievable with radiotherapy, including repeat courses.
- Surgical intervention may be necessary for refractory cases.