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Updated: Aug 27, 2026

Skeletal Muscle Gender Dimorphism from Proteomics
Published on: December 14, 2011
Characterization of protein kinase system in human skeletal muscle
Abstract:
The properties and distribution of basal and cyclic nucleotide stimulated protein kinases have been studied in normal and diseased human muscles. In particulate fraction of muscles from neurogenic atrophy the PK activity is remarkably lower than in control tissues, whereas in the cytosol of the same tissues an increase of enzyme activity was observed. In Duchenne dystrophy the PK activities were slighly lower than in controls both in particulate and in soluble fractions. The authors suggest that the altered subcellular distribution found in neurogenic atrophy might be due to the loss of nerve trophic control.
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