Nummular keratitis associated with infectious mononucleosis

Area of Science:

• Ophthalmology
• Virology
• Infectious Diseases

Background:

• Infectious mononucleosis, a common illness caused by the Epstein-Barr virus (EBV), is frequently subclinical.
• Nummular keratitis is an inflammatory condition of the cornea, often with an unknown cause (idiopathic).

Observation:

• A 16-year-old male presented with severe infectious mononucleosis and rising Epstein-Barr virus titers.
• The patient concurrently developed nummular keratitis, suggesting a potential link to the viral illness.

Findings:

• The case suggests a possible association between Epstein-Barr virus infection and the development of nummular keratitis.
• This association may be relevant in cases where infectious mononucleosis is subclinical.

Implications:

• Clinicians should consider EBV infection as a potential cause for idiopathic nummular keratitis.
• Further research is warranted to confirm the link between EBV and nummular keratitis, especially in subclinical presentations.