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Arthritis associated with common viral infections: mumps, coxsackievirus, and adenovirus

A S Bayer

    Postgraduate Medicine
    |July 1, 1980
    PubMed

    Insights

    Viral infections like mumps, coxsackievirus, and adenovirus can cause puzzling arthritis. This arthritis may be migratory or resemble juvenile rheumatoid arthritis, often requiring only supportive care.

    Area of Science:

    • Virology
    • Rheumatology
    • Pediatrics

    Background:

    • Common viral infections can present with complex rheumatological manifestations.
    • Arthritis complicating mumps, coxsackievirus, and adenovirus infections poses diagnostic challenges.
    • Mumps arthritis often appears after initial symptoms resolve, complicating early identification.

    Purpose of the Study:

    • To elucidate the enigmatic nature of arthritis associated with common viral infections.
    • To describe the clinical presentation and course of viral-induced arthritis.
    • To differentiate viral arthritis from other rheumatological conditions like Still's disease.

    Main Methods:

    • Clinical case review and analysis of patients presenting with viral infections and arthritis.
    • Epidemiological data analysis of arthritis incidence following viral infections.
    • Symptomatic and laboratory data correlation to understand pathogenesis.

    Main Results:

    • Mumps arthritis typically presents 1-2 weeks after parotitis resolution, often as migratory polyarthritis requiring supportive care.
    • Coxsackievirus and adenovirus infections can trigger a Still's disease-like juvenile rheumatoid arthritis.
    • Viral-associated polyarthritis can be persistent or recurrent, sometimes unresponsive to anti-inflammatory drugs.

    Conclusions:

    • Viral arthritis is a significant, albeit often overlooked, cause of joint inflammation.
    • Understanding the specific viral triggers and their distinct arthritic syndromes is crucial for accurate diagnosis and management.
    • Further research into the mechanisms of viral-induced arthritis may reveal novel therapeutic targets.

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