[Clinico-radiological and functional correlations in endothoracic sarcoidosis]

A total of 35 cases of endo-thoracic sarcoidosis have been studied, of which 18 were confirmed histopathologically on bioptic samples. The analysis of the cases revealed the predominance of young subjects. The reactivity of PPD on cutaneous testing was negative in 60 percent of the cases, in accordance with the antimycobacterial fluorescent antibodies test. The insidious onset and evolution are noted, and the fact that the diagnosis was made on the occasion of routine investigations. Correlation of clinical signs with the radiologic aspects did not reveal significant data, but correlation with functional tests has revealed in 8 out of 11 cases presenting with dyspnoea an alteration of the respiratory function (an obstructive, a restrictive or a mixed syndrome). The importance of the diagnosis is stressed, in view of the application of treatment, that should not be delayed.