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Sacrococcygeal paciniomas.

P M Bale

    Pathology
    |April 1, 1980
    PubMed
    Summary
    This summary is machine-generated.

    Two infant Paciniomas, distinct from neurofibromas, were surgically removed due to spinal deformities. These rare tumors, possibly malformations, were found connected to the spinal dura via sacral dimples and spina bifida.

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    Area of Science:

    • Neuropathology
    • Developmental biology
    • Pediatric surgery

    Background:

    • Paciniomas are rare tumors originating from Pacinian corpuscles.
    • Spinal deformities in infants can have various underlying causes.
    • Understanding the nature of congenital spinal lesions is crucial for diagnosis and treatment.

    Observation:

    • Two cases of well-differentiated Paciniomas were resected from infants presenting with spinal deformities.
    • The tumors appeared as thick cords extending from a sacral dimple through an occult spina bifida to the spinal dura.
    • Histological examination of control sacrococcygeal regions from 15 infants revealed Pacinian corpuscles in 7, typically near the coccyx and not numerous.

    Findings:

    • The resected Paciniomas showed no resemblance to neurofibromas.

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  • The lesions were characterized as either a malformation or a hamartomatous overgrowth.
  • Pacinian corpuscles are present in the sacrococcygeal region of infants, but typically sparse.

    • Implications:

    • These findings suggest Paciniomas can present as congenital spinal malformations.
    • Further research is needed to elucidate the developmental origin of Paciniomas.
    • This study contributes to the differential diagnosis of pediatric spinal tumors and congenital anomalies.