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A normal cumulative conception rate after human pituitary gonadotropin
Fertility and Sterility
|October 1, 1980
Summary
Human pituitary gonadotropin successfully induced ovulation in 93% of women, with 75% conceiving. This treatment offers a conception rate comparable to the general population for infertility.
Area of Science:
- Reproductive endocrinology and infertility treatment.
Background:
- Ovulation induction is a key treatment for infertility.
- Human pituitary gonadotropin (hPG) has been used to stimulate ovulation.
Purpose of the Study:
- To evaluate the efficacy of human pituitary gonadotropin in inducing ovulation and achieving conception.
- To assess factors influencing treatment success, including patient history and reasons for non-conception.
Main Methods:
- Prospective treatment of 40 consecutive women with human pituitary gonadotropin.
- Tracking ovulation and conception rates.
- Analysis of patient characteristics and reasons for treatment failure.
Main Results:
- Ovulation was induced in 37 patients (93%).
- Thirty patients (75%) conceived at least once.
- Cumulative conception rates matched the general population.
- Women with a history of anorexia nervosa had shorter time-to-pregnancy.
Conclusions:
- Human pituitary gonadotropin is effective for ovulation induction and achieving conception.
- Realistic goals include universal ovulation induction and population-level conception rates.
- Patient selection and adherence are crucial for successful outcomes.