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[The menopause and its problems (author's transl)].

J Salat-Baroux

    La Semaine Des Hopitaux : Organe Fonde Par L'Association D'Enseignement Medical Des Hopitaux De Paris
    |September 18, 1980
    PubMed
    Summary
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    Menopause, characterized by anovulation and cessation of menses, is defined alongside perimenopause and premenopause. Understanding its complex hormonal and social factors may benefit from exploring estrogen therapy.

    Area of Science:

    • Reproductive endocrinology and the study of female aging.
    • Exploration of the physiological and hormonal changes during the menopausal transition.

    Context:

    • The menopause is defined by the cessation of menstruation and ovulation, with perimenopause encompassing the entire menopausal transition.
    • Social and demographic factors, including rising average age and societal roles for women, are considered.
    • Current understanding of physiopathological factors involves ovarian insensitivity and hormonal shifts, with intact hypothalamo-pituitary axis.

    Purpose:

    • To clarify the definitions of menopause, perimenopause, and premenopause.
    • To examine the social and demographic aspects influencing women's menopausal experiences.
    • To investigate the underlying physiopathological mechanisms and potential therapeutic interventions.

    Summary:

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  • The menopausal transition is defined by specific reproductive events and hormonal changes, including estrogen secretion during premenopause.
  • Societal factors and the average age of menopause are discussed, alongside the need for social engagement for women.
  • Physiopathological understanding points to ovarian insensitivity and potential catecholamine interactions, suggesting estrogen therapy as a possible avenue.

    • Impact:

    • Provides a clearer definition of menopausal stages for clinical and research purposes.
    • Highlights the importance of social and demographic contexts in women's menopausal health.
    • Suggests further research into hormonal balances and the potential benefits of estrogen therapy for managing menopausal symptoms.