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[Menopausal risk factors (author's transl)].

J C Colau, J Y Couturier

    La Semaine Des Hopitaux : Organe Fonde Par L'Association D'Enseignement Medical Des Hopitaux De Paris
    |September 18, 1980
    PubMed
    Summary

    Menopausal disorders are linked to hormonal changes like luteal insufficiency and hyperestrogenism, increasing risks for menstrual issues and gynecological conditions. Post-menopause, reduced estrogen and increased FSH/LH levels elevate cancer risks, necessitating careful evaluation of estrogen

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    Area of Science:

    • Gynecology
    • Endocrinology
    • Oncology

    Context:

    • Menopausal disorders often present with luteal insufficiency and relative hyperestrogenism.
    • These conditions can lead to a worsening of the menstrual syndrome and cycle changes.
    • Post-menopause, reduced estrogen levels correlate with increased risks of certain cancers.

    Purpose:

    • To outline the risks associated with menopausal disorders.
    • To highlight the connection between hormonal imbalances and gynecological health issues.
    • To emphasize the importance of evaluating estrogen's role in endometrial cancer.

    Summary:

    • Menopausal disorders involve luteal insufficiency and hyperestrogenism, increasing risks for menstrual syndrome, cycle changes, and genital hemorrhage.
    • Post-menopause, reduced estrogen and increased FSH/LH levels elevate cancer risks, particularly endometrial, vulvar, cervical, and breast cancers.
    • Cardiovascular risks in untreated menopausal women are debated, as are the benefits of estrogen therapy.

    Impact:

    • Informs clinical assessment of menopausal women, focusing on hormonal imbalances and associated risks.
    • Provides a foundation for understanding the link between estrogen levels and gynecological cancer development.
    • Guides further research into the benefits and risks of hormone therapy during and after menopause.

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