Retinoblastoma in a microphthalmic eye

A case of simultaneous occurrence of microphthalmus and retinoblastoma in an eye removed from a 1-year-old monozygote twin with bilateral retinoblastoma, is reported. The other eye was of normal size, and was treated with irradiation (local application of Stallard disc). This case seems to be the first one published showing that one cannot be usre of the absence of tumours in small eyes although it is extremely rare.