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Retinoblastoma in a microphthalmic eye.

I Axelsen

    Ophthalmologica. Journal International D'Ophtalmologie. International Journal of Ophthalmology. Zeitschrift Fur Augenheilkunde
    |January 1, 1978
    PubMed
    Summary

    This rare case report details simultaneous microphthalmos and retinoblastoma in one eye of a twin with bilateral retinoblastoma. It highlights that small eyes, though rarely, can still harbor tumors.

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    Area of Science:

    • Ophthalmology
    • Pediatric Oncology
    • Genetics

    Background:

    • Bilateral retinoblastoma is a significant pediatric malignancy.
    • Microphthalmos, a congenital condition of small eye size, can be associated with various ocular abnormalities.

    Observation:

    • A case of simultaneous microphthalmos and retinoblastoma in a single eye of a 1-year-old monozygotic twin is presented.
    • The twin presented with bilateral retinoblastoma; the affected eye was microphthalmic, while the other was of normal size and treated with irradiation.

    Findings:

    • This case represents the first reported instance of co-occurrence of microphthalmos and retinoblastoma in the same eye.
    • The findings underscore the possibility, albeit rare, of tumor presence in microphthalmic eyes.

    Implications:

    • The report challenges assumptions about the absence of tumors in microphthalmic eyes.
    • It emphasizes the need for thorough ocular examination in cases of microphthalmos, especially in the context of genetic predispositions like retinoblastoma.

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