[An experimental study of veralipride (author's transl)]

The administration of doses of 0,001, 0, 01, 0,1, and 1 mg/kg/day of veralipride to female rats produces a dose-related blocking effect on dioestrus. No histological changes are noted in the genital tract and mammary gland tissues after 0,001 and 0,01 mg/kg/day. Doses of 0,1 and 1 mg/kg/day block ovulation and the resulting estrogen impregnation modifies the appearance of the uterine glands and vaginal epithelium. Mammotropic effects, seen as a moderate hyperplasia but without galactogenic secretion, occur after 1 mg/kg/day only.