[Combined Wilms' tumor therapy (author's transl)]

From 1967 to 1979, 40 children with Wilms' tumor were given a therapy comprising irradiation, operation and chemotherapy. Till 1972 preoperative irradiation was performed delivering a dose of 20 Gy followed by operation and actinomycin-D. The postoperative irradiation dose was 20 or 30 Gy. Of 22 patients died 7. Since 1973, therapy depends on age and tumor volume and consists in a combination of multidrug therapy, operation and irradiation (25 to 35 Gy). Of 19 children, 18 are still alive. No irradiation was given to patients younger than 1 year in stages I and II and to older children in stage I.