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Endogenous substrate for cyclic AMP-dependent protein kinase in adrenocortical polyadenylated messenger
Science (New York, N.Y.)
|December 5, 1980
Abstract:
An endogenous polysomal cyclic AMP-dependent protein kinase specifically phosphorylates a 150,000-dalton peptide bound to an adrenocortical polyadenylated messenger ribonucleoprotein complex. There is a possibility that this protein is a physiological substrate of cyclic AMP-dependent protein kinase and that the phosphorylation and dephosphorylation of this substrate may be important in the translation control of adrenal polyadenylated messenger RNA.