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Anti leukemia activity (Dunning ascitic) of 6-mercaptopurine and its metallo complexes in rats

S M Skinner, J M Swatzell, R W Lewis

    Research Communications in Chemical Pathology and Pharmacology
    |January 1, 1978
    PubMed

    Abstract:

    Six-mercaptopurine and its Pt, Pd and Bi complexes were used at various dosage levels to treat Dunning ascitic leukemia in rats. Significant anticarcinogenic activity was found in all compounds with toxicity apparent at the highest dosage level of all but the platinum compound.

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