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Enhanced macrophage and natural killer cell antitumor activity by various molecular weight maleic anhydride divinyl

A Bartocci, V Papademetriou, M A Chirigos

Journal of Immunopharmacology

|January 1, 1980

Abstract:

A series of Maleic anhydride divinyl ether (MVE) polyanions, synthesized with molecular weight ranging from 12500 to 52600, were found capable of enhancing macrophage tumoricidal activity of MBL-2 leukemia cells. These agents also augmented Natural Killer cell activity against the YAC lymphoma and M109 adenocarcinoma cell lines.

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