Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Endemic Balkan nephropathy (author's transl)].

B Markovic

    La Nouvelle Presse Medicale
    |November 15, 1980
    PubMed
    Summary

    Endemic Balkan nephropathy (EBN) is a progressive kidney disease. Early diagnosis is aided by detecting urine concentration loss and elevated beta-2 microglobulin levels.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    A new model to determine lipophilicity of 1,2-ethanediamine-<i>N,N'</i>-di-2-(3-cyclohexyl)propanoic acid and 1,3-propanediamine-<i>N,N'</i>-di-2-(3-cyclohexyl)propanoic acid derivatives with antiproliferative activity by combining shake flask procedure and UHPLC-MS method.

    Die Pharmazie·2018
    Same author

    Brain and art: illustrations of the cerebral convolutions. A review.

    Folia morphologica·2014
    Same author

    Lack of mitochondrial DNA structure in Balkan donkey is consistent with a quick spread of the species after domestication.

    Animal genetics·2013
    Same author

    The effect of lipophilicity on the hepatobiliary properties of iminodiacetic acid derivatives in the conditions of hyperbilirubinemia.

    Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine·2013
    Same author

    10 ps resolution, 160 ns full scale range and less than 1.5% differential non-linearity time-to-digital converter module for high performance timing measurements.

    The Review of scientific instruments·2012
    Same author

    The expression of cytokine messenger-rnas in clear cell acanthoma.

    International journal of oncology·2011

    Area of Science:

    • Nephrology
    • Toxicology
    • Pathology

    Context:

    • Endemic Balkan nephropathy (EBN) is a chronic interstitial nephritis affecting families.
    • Diagnosis is challenging in early stages, often presenting with anemia and altered plasma biochemistry.

    Purpose:

    • To detail the clinical presentation, diagnostic markers, and pathological findings of EBN.
    • To explore the potential etiological link between silicate exposure and EBN.

    Summary:

    • EBN is a slowly progressive chronic interstitial nephritis with early signs including anemia, elevated plasma amino acids, alkaline phosphatases, and globulins.
    • Key early diagnostic indicators are impaired urine concentration and high urinary beta-2 microglobulin levels.
    • Renal biopsy reveals interstitial sclerosis, immunoglobulin deposits, and characteristic mitochondrial abnormalities in proximal tubule cells.

    Impact:

    • Highlights the importance of early diagnostic markers for EBN.
    • Suggests chronic silicate intoxication from contaminated drinking water as a probable etiological factor.
    • Provides insights into the pathological mechanisms and potential systemic effects of EBN.

    Related Experiment Videos