Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Biosynthesis of polypeptide hormones].

P Crine, N G Seidah, F Gossard

    Revue Canadienne De Biologie
    |March 1, 1980
    PubMed
    Summary

    Hormone production involves pre- and prohormones, which are precursor proteins. These precursors undergo processing to yield active hormones like parathyroid hormone, insulin, and adrenocorticotropin.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Poster - Thurs Eve-39: Full 3D dose calculation for total body irradiation: A comparison study between treatment planning systems in homogeneous and heterogeneous conditions.

    Medical physics·2017
    Same author

    H.E.S.S. Limits on Linelike Dark Matter Signatures in the 100 GeV to 2 TeV Energy Range Close to the Galactic Center.

    Physical review letters·2016
    Same author

    Search for Dark Matter Annihilations towards the Inner Galactic Halo from 10 Years of Observations with H.E.S.S.

    Physical review letters·2016
    Same author

    Relationship between testosterone, estradiol and circulating PCSK9: Cross-sectional and interventional studies in humans.

    Clinica chimica acta; international journal of clinical chemistry·2015
    Same author

    Constraints on an annihilation signal from a core of constant dark matter density around the milky way center with H.E.S.S.

    Physical review letters·2015
    Same author

    Genetic deficiency for proprotein convertase subtilisin/kexin type 2 in mice is associated with decreased adiposity and protection from dietary fat-induced body weight gain.

    International journal of obesity (2005)·2010

    Area of Science:

    • Biochemistry
    • Molecular Biology
    • Endocrinology

    Context:

    • Hormone biosynthesis is a complex process involving precursor molecules.
    • Understanding precursor structures is key to deciphering hormonal regulation.

    Purpose:

    • To discuss the structure, characteristics, and function of polypeptide hormone precursors.
    • To examine examples including parathyroid hormone, insulin, and a common precursor for adrenocorticotropin and beta-lipotropin.

    Summary:

    • Polypeptide hormones are synthesized from pre- and prohormone precursors.
    • Examples like parathyroid hormone and insulin illustrate precursor processing.
    • A shared precursor for adrenocorticotropin and beta-lipotropin undergoes proteolytic cleavage into biologically active peptides.

    Impact:

    • Elucidates the fundamental mechanisms of hormone production.
    • Provides insights into the generation of diverse bioactive peptides from single precursors.
    • Highlights the importance of proteolytic processing in endocrine signaling.

    Related Experiment Videos