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Updated: Aug 19, 2026

Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
Published on: March 19, 2019
Familial chronic mucocutaneous candidiasis successfully treated with oral ketoconazole
Abstract:
A father and son, both suffering from chronic mucocutaneous candidiasis, were successfully treated with oral ketoconazole, a water-soluble imidazole compound. No toxic side-effects occurred during treatment. Treatment was given for about 8 months with diminishing does of ketoconazole. The disease cleared completely about half-way through the course of treatment and did not relapse within 1 month of discontinuing the drug. The only immunological abnormality was a depression in vitro of neutrophil chemotaxis. This became normal during therapy and was regarded as being a result of the disease and not as its cause.
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