[Serotypes of herpes simplex virus and their association with cervical cancer]

Comparative studies of some properties of Herpes simplex viruses type I and II and their ability to reproduce latent infection in vitro revealed no essential differences between them. Virus-neutralizing and hemagglutinating antibodies to the virus type II are detected reliably more frequently in cervical cancer patients than in healthy ones. Forty six per cent of cervical cancer patients and thirty nine per cent of healthy females along with antibodies against the virus of serotype II showed a specific cellular response, which was demonstrated in the reaction of leucocyte migration inhibition. In patients with dissemination of the disease there is an inhibited cell immunity to Herpes virus without changing of the humoral resistance.