[Substituted benzamides]

The comparison of the therapeutic effects of three molecules belonging to the substituted benzamide family allows the following observations: --the three products are generally well tolerated by the organism; --at sufficient doses they act as a major tranquilizers: -sulpiride is chiefly a disinhibitor but also has antipsychotic properties; -sultopride is at first somewhat sedative, especially when given parenterally, then antipsychotic, and little by little desinhibiting; -GRI 16-65 is "soothing", "euphoriant", "sociabilizing", as well as antipsychotic. Effect of reintegration in reality seems to constitute a common characteristic of these three products.