Aggressive fibrous histiocytoma of perioral soft tissues: report of case
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Updated: Oct 5, 2026

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Abstract:
A rare case of aggressive fibrous histiocytoma is presented to alert the clinician to the existence of such a lesion and its ability to develop as a perioral soft tissue tumor. The research on these lesions clearly demonstrates the lability of their biologic potential. The clinical characteristics, symptoms, and histiologic makeup are reviewed and further reinforce the conclusion that careful microscopic study and thorough longterm followup to adequate surgical treatment are currently the only effective means in the management of these tumors. Continued reports from clinicians and researchers will perhaps satisfy many questions concerning this curious and potentially destructive and lethal group of lesions.
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